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Late Effects

Hearing Loss (Ototoxicity)

Hearing loss usually affects both ears and is irreversible.
It can be caused:

  • By cisplatin, which is one of the most active drugs used in osteosarcoma
  • If ifosfamide (another drug) is given before or at the same time as cisplatin
  • By the intensity of the dosage schedule
  • If other drugs were given at the time of therapy

 

 

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