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Treatment for Removable Tumors

Patients with a removable tumor will first undergo surgery to remove the tumor, and then will be treated with chemotherapy and radiation.

Surgery

Surgery should be done by a pediatric surgeon or pediatric urologist that is used to taking care of children with cancer. After the surgeon has checked the whole abdomen for any additional signs of tumor, the whole kidney including the tumor is usually removed. In addition, the surgeon will take out some lymph nodes to check whether or not any tumor is present in these lymph nodes.

Chemotherapy

After surgery, patients are treated with chemotherapy. Chemotherapy is used to kill any tumor cells left over after surgery.

Chemotherapy is determined by your child's tumor stage. Two protocol regimens are used to treat clear cell sarcoma:

Patients with stage I-IV CCSK are most commonly treated with Regimen I.
Chemotherapy drugs used are cyclophosphamide, etoposide, vincristine, and doxorubicin.

Patients with stage IV CCSK who choose to participate in the clinical trial by the Children's Oncology Group, are treated with Regimen UH1.
Chemotherapy drugs used are cyclophosphamide, etoposide, vincristine, and doxorubicin as well as carboplatin.

Clinical trials offer the most up-to-date chemotherapy treatments with the best-known results for improvement or cure of clear cell sarcoma. The majority of young cancer patients decide to enter into a Phase III clinical trial such as the one offered by the Children's Oncology Group.

More about the newest clinical trials.

Radiation Therapy

Radiation therapy is usually given during the first week of chemotherapy and very soon after removal of the tumor. This minimizes the chance for any tumor cells that might have been left behind, to grow.