Chemical Synthesis & Organic Drug Lead Development Services
The services of the Chemical Synthesis Core include:
Custom Syntheses of Investigator-Requested Compounds
- Literature-cited compounds (including patented agents)
- Compounds discovered through high-throughput screening
- Experimental agents
- Focused libraries
Medicinal Chemistry Support
- Improved ADMET (adsorption, distribution, metabolism, excretion, toxicity) properties of lead compounds to improve biological activity
- Lead optimization (SAR analysis)
- Database searching and data mining of drug discovery targets
- Insight on the patentability of chemical matter
- Chemical informatics