Indiana University Melvin and Bren Simon Cancer Center

Researchers

Research Programs Member Directory Become a Member Shared Facilities Angiogenesis, Endothelial & Pro-Angiogenic Cell Core Behavioral and Cancer Control Recruitment Core Biological Microscopy Biostatistics & Data Management Bio-Plex Center for Computational Biology and Bioinformatics Chemical Genomics Clinical Pharmacology Analytical Core Services Policies & Procedures Examples Contact Clinical Research Office Flow Cytometry In Vivo Biomedical Imaging In Vivo Therapeutics Protein Analysis Research Center Therapeutic Validation Tissue Procurement and Distribution Transgenic and Knock-Out Mouse Translational Genomics Funding Opportunities Research Resources Signature Centers

You are here: HOME > Researchers > Facilities > Clinical Pharmacology Analytical Core > Services

Clinical Pharmacology Analytical CoreServices

Access to high-end instrument for quantification of drugs and metabolites is an invaluable resource for all cancer investigators in the IUSCC.  The core has three of these instruments (HPLC-MS/MS; API 4000, Thermo Quantum Ultra, and API 3200) for drug quantification.

Compounds that have been quantified by CPAC include anticancer agents such as:

5-azacytidine carboplatin decitabine docetaxel erlotinib

etoposide gemcitabine medroxyprogesterone acetate mitomycin C oxaliplatin

paclitaxel and metabolites teniposide temozolomide vincristine and metabolite vinorelbine

Other compounds that have been quantified by CPAC include:

aprepitant clarithromycin granisetron midazolam and metabolites norethindrone

norgestimate and metabolites ondansetron triazolam temazepam

Additionally, CPAC now offers assessments of binding of drugs to plasma proteins.

List of Publically known drugs with Methods already developed (COMING SOON)