Indiana University Melvin and Bren Simon Cancer Center

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In Vivo Therapeutics Policies & Procedures

Request for services

To request mice from the on-site breeding facility, fill out the appropriate online mouse request form. Contact Karen Pollok (kpollok@iupui.edu) for detailed information on in vivo services and pricing or to set up a consultation and study design meeting.    

F1 Request Form

NOD SCID Request Form

NS2 Request Form

BoyJ Request Form

Radiation Services Scheduler 

Fees

The core is funded, in part, by grants and contracts of the investigators who utilize the facility. All IUSCC members receive discounted rates. Due to the variety of in vivo models and drug regimens requested, the specific costs of a study will be calculated once the study design is finalized. 

Acknowledgment, authorship, collaboration

All research work performed by the IVT core should be acknowledged in all ensuing publications. Fees paid for services provided by the core should not negate the potential of co-authorship by core scientists. These acknowledgements and achievements are important for the existence and continued funding of the core facility. Given that many validation procedures require advanced intellectual involvement by the core’s scientists (examples listed below), it is expected that this acknowledgement will be in the form of co-authorship according to the guidelines for authorship recommended by the International Committee of Medical Journal Editors. 

 

IVT scientists performing one or more of the following tasks meet the criteria for authorship:

• Literature review and providing assistance in selecting/conceiving the experiments appropriate for the study goals
• Experimental design
• Assay development/optimization
• Data analysis and interpretation of data, or both
• Preparation of pertinent sections/figures for the manuscript and revisions to address reviewer concerns/questions

All contributions that do not meet the criteria for authorship should be listed in the acknowledgments section. Examples of the tasks requiring an appropriate mention in the acknowledgment section are:

• Mere collection of data (e.g., Flow cytometry) using PI-provided protocols that require no further optimization and/or trouble-shooting.
• Mere collection of in vivo study data (no data analysis or interpretation by core scientists.
• Irradiation and/or transplant of bone marrow cells
• Routine sample processing (e.g., serum/plasma separation, isolation of PBMCs from blood)

Distribution of mice for studies not implemented by core personnel:

• If using mice bred by our facility, please include the following acknowledgement: Mice were obtained from the on-site breeding colony maintained by the In Vivo Therapeutics Core of the Indiana University Melvin and Bren Simon Cancer Center
• Strains we maintain:

NOD/scid: NOD.CB17-Prkdcscid/J

NSG: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

Boy J: B6.SJL-Ptprca Pepcb/BoyJ

C57/Boy J F1: C57BL/6J x B6.SJL-Ptprca Pepcb/BoyJ