Research Program Membership

Full Member of

• Experimental and Developmental Therapeutics

Research Interests

My research interest is focused on development of novel magnetic resonance (MR) spectroscopy (MRS) and imaging (MRI) techniques for noninvasive monitoring of tissue physiology, metabolism and other molecular events. 1H MRI has taken the center-of-stage in clinical radiology primarily due to its ability to image soft tissue with very high contrast. With advancements in high field MR systems it is now possible to monitor less abundant nuclei, such as 23Na, 30P, 13C, and 14N with relatively high temporal and spatial resolution. These nuclei can provide a vast amount of metabolic and physiologic information noninvasively. We are excited about the novel multinuclear MR techniques to predict and monitor response to experimental therapies using the state-of-the-art high-field (9.4T) animal MR systems at the Imaging Science Center.

Publications

PubMed Listing »

Education

Post-doctoral Fellowship UT Southwestern Medical Center, Dallas, TX 1988-1989

Ph.D. University of Delaware, Newark, DE 1984-1988