Member Biography

Todd C. Skaar Ph.D.
Associate Research Professor
Department of Medicine
Division of Clinical Pharmacology
School of Medicine
WD Myers, W7123; 1001 W 10th St
Indianapolis, IN 46202
Phone: (317) 630-2695
Research Program Membership
Full Member of
Research Interests
My current research focuses on clinical pharmacology with an emphasis on breast cancer and endocrine therapies used to treat and prevent breast cancer. Recently, we have been identifying genes in breast cancer cells that mediate the effects of antiestrogens and retinoids and future experiments are designed to determine their usefulness as tools for optimizing the use of these drugs in patients. Furthermore, we are studying the cytochrome P450 enzymes and how they are involved in the metabolism of therapeutic drugs. Currently, we are focusing on the pharmacogenetic aspects of these drugs/genes and how they might be useful in the overall utilization of these therapies.
Publications
Education
Post-doctoral Fellowship Georgetown University 1992-1997
Ph.D. Pennsylvania State University 1988-1992
