Translational Research Core

The Translational Research Core (TRC) was established to help clinical researchers develop and utilize laboratory correlatives in their research. The TRC can assist researchers and clinical trails with:

  • Project Startup
    • Identifying relevant laboratory correlatives and collaborative labs
    • Development of standard operating procedures and lab manuals
    • Development of budgets
    • Project logistics
  • Sample Collection and Management
    • Sample retrieval
    • Sample labeling and management
    • Coordination with other labs and/or Cores for sample storage and analysis
    • Shipment of samples to other sites
  • Sample Processing and Analysis
    • Processing
      • Plasma and serum separation
      • PBMC isolation
      • Nucleic acid extraction from cells and tissues
      • Protein isolation from cells and tissues
    • Laboratory Analysis
      • ELISAs
      • Flow Cytometry
      • Western Blot
      • Protein/nucleic acid quantification
      • Unique assay development/assay optimization 
  • Sample Storage
    • Short term ambient, freezer, and liquid nitrogen
    • Coordination with SSF or other biorepository