Experimental & Developmental Therapeutics

Therapeutics LabThe mission of the Experimental and Developmental Therapeutics (EDT) research program is to promote, develop and exploit mechanism-based research for improved therapy of human cancer with a “bedside-to-bench-to-bedside approach.”

The program has two themes:

Theme 1: Novel cancer-selective targets and antitumor agents towards therapeutic development

  • Aim 1: To investigate roles of DNA repair, genetic instability and maintenance.
  • Aim 2: To elucidate targets in cell signaling cascades and metabolism.

Theme 2: Translation of mechanism-based therapies to the clinic

  • Aim 1: To conduct IND-enabling preclinical studies of antitumor agents.
  • Aim 2: To conduct mechanism-based clinical trials.